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Incorporating the sample correlation into the testing of two endpoints in clinical trials.
In this article, published in the Journal of Biopharmaceutical Statistics, Sanat Sarkar, Dror Rom and Jaclyn McTague introduce an improved Bonferroni method for testing two primary endpoints in clinical trial settings using a new data-adaptive critical value that explicitly incorporates the sample correlation coefficient.
NBCD and Prosoft Clinical enter acquisition-agreement under the Sanos Group
February 1, 2021 Prosoft Clinical (Prosoft), a full-service CRO specialized in dermatology based in Wayne, PA, USA and NBCD, a global full-service CRO specialized in osteoarthritis, based in Copenhagen, Denmark have entered into an agreement to share resources with the potential for a future merger under Sanos Group. Prosoft Clinical has a strong US presence, and capabilities that in addition to classic CRO services include a proprietary electronic data capture (EDC) system, and specialty
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